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SY-20F R&D-Stoppering

The pilot-scale freeze dryer (R&D) in this series replicates the functionality of production-scale freeze dryers, making it suitable for optimizing industrial freeze-drying parameters. It can be used for process scale-up, approaching production-scale parameters. Whether in early-stage research and development or later in the process scale-up phase, it can provide high-performance process parameters.
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Product Advantage


1. Meeting Special Sample Process Requirements:

In the fields of pharmaceuticals, life sciences, and specialized materials freeze-drying applications, some products have critical temperature values Te, Tm, Tc, Tg1 that are lower, even below the control values of pre-freezing and sublimation in conventional freeze dryers. SONYAN Freeze Dryer achieve breakthroughs in special sample freeze-drying by employing targeted structural design, functional upgrades, and process optimizations at the equipment level.


2. Professional Tray and Cold Trap Technology Production for Uniform Drying:

SONYAN Freeze Dryer employ specialized tray and cold trap technology production to ensure uniform drying results. The stable control system and user-friendly operation facilitate process optimization and drying effect verification.

3. In-situ vacuum freeze dryer with automated freeze-drying process.

4. Main unit consists of a dual-chamber system with a cold trap and drying chamber.

5. Easy-to-disassemble machine body with maintenance access, no tools required.

6. Each layer is equipped with independent sample temperature probes.

7. Cold trap cooling rate: -20°C to -40°C in ≤20 minutes.

8. Heating and cooling rate of 1°C per minute.

9. Sublimation curve control switch for switching between stepwise and linear temperature control.

10. Shelf temperature control accuracy of ±1°C.

11. PLC controller with PID temperature regulation.

12. Nitrogen gas filling system for drying with inert gas.

13. Comprehensive maintenance reminder features.

14. Multiple safety protections for vacuum and refrigeration systems.

LGJ-20F压盖型干燥室


 

Technical Parameters


Model


SY-20F

Stoppering

SY-30F

Stoppering

SY-50F

Stoppering

SY-100F

Stoppering

Freeze Drying Area

0.2

0.3

0.5

1.15

Cold Trap Temperature

<-75 (no-load)

Vacuum Level

Pa

≤1 (no-load)

Shelf Temperature Range

-55-+70 (no-load)

Maximum ice capacity

kg/24h

≥6

≥8

≥10

≥15

Number of Shelf Layers

pcs

2+1

3+1

3+1

4+1

Material Tray

mm

400×270

300×340

410×410

480×600

Shelf Spacing

mm

100

70

100

100

Overall Power

kW

4

5.5

6.5

7.5

Weight

kg

300

400

800

1000

Dimensions

mm

1033×781×1704

853×1272×1679

911×1405×1983

1823×1144×2014mm

Loadable Materials

L/kg

2

3

5

11

Loadable Vials

pcs

Ф12mm:1554

Ф12mm:2187

Ф12mm:3705

Ф12mm:8624

pcs

Ф16mm:868

Ф16mm:1200

Ф16mm:2058

Ф16mm:4788

pcs

Ф22mm:440

Ф22mm:654

Ф22mm:1050

Ф22mm:2460

Defrost Mode

-

Electric Defrost

Electric Defrost

Electric Defrost

Electric Defrost

Safety Devices

-

Audible Alarm, Emergency Stop Switch, Overpressure Protection

Power Supply

-

Single-phase 3-wire, 220 volts

Three-phase 5-wire, 380 volts

Optional features:

· Vacuum level control

· Eutectic point testing

· Chamber isolation valve

· Remote control via PC or mobile app

· Imported vacuum pumps

· Anti-oil backflow solenoid valve

· Oil mist filter


Product Uses


It is not only suitable for the freeze-drying of bulk (liquid, paste, solid) conventional substances but also for the drying of substances packaged in vials. During the freeze-drying preparation, materials can be portioned into vials as needed, sealed with bottle caps, and then subjected to freeze-drying. After drying, the stoppering device can be used to tightly seal the vial caps. This process helps prevent secondary contamination and reabsorption of moisture, making it easy to store the materials for an extended period.


Product Operate Guide


The control system of this machine features a large touchscreen, providing convenient, straightforward operation with powerful functionality. Each screen displays a wealth of data in an intuitive and clear manner. It can store hundreds of temperature control programs, with each program allowing for the configuration of up to 36 segments.

Advanced fuzzy PID control algorithms ensure precise and stable temperature control. During automatic temperature control, you can modify temperature parameters and skip segments as needed, offering flexibility in operation. The system controls shelf temperatures according to pre-set parameters. Multiple stability measures are incorporated into the system, ensuring stable and reliable operation.


FAQ


1. What is a stoppering freeze dryer, and how does it differ from other freeze dryers?

A stoppering freeze dryer is a type of freeze-drying equipment that is designed specifically for sealing containers, such as vials or bottles, after the freeze-drying process. It differs from other freeze dryers in that it includes a stoppering mechanism to create a hermetic seal on the containers, preserving the integrity of the dried product and preventing contamination. This feature is particularly valuable for pharmaceutical and biotech applications.


2.What are the advantages of using a stoppering freeze dryer?

The main advantage of a stoppering freeze dryer is its ability to provide a sealed container for the dried product. This is crucial for maintaining product stability, preventing moisture reabsorption, and ensuring product integrity. It is commonly used in industries where product quality and long-term storage are critical, such as pharmaceuticals, biotechnology, and food.


3. Can a stoppering freeze dryer be used for laboratory-scale applications?

Yes, stoppering freeze dryers are available in various sizes, including laboratory-scale models. These smaller units are ideal for research and development purposes, allowing scientists to conduct experiments and develop freeze-drying processes while maintaining the benefits of container sealing. They are commonly used in pharmaceutical research and biotechnology laboratories to optimize formulations and ensure product quality.


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